Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 6 reviews · Neuromuscular

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 7.1%Low 3 · 21.4%Moderate 4 · 28.6%High 6 · 42.9%

Intervention not reported

Serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)

It is very uncertain whether the intervention changes serious adverse eventsClinical manifestation and laboratory… (very low certainty).

1 finding from 1 review

Intensive insulin therapy vs conventional insulin therapy

Serious adverse events, ‐ in total population randomised ‐ hypoglycaemia · critically ill patients

Intensive insulin therapy leads to higher serious adverse events, ‐ in total population randomised ‐… compared with conventional insulin therapy (high certainty).

1 finding from 1 review

Intervention not reported

Non‐serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)

The intervention showed no clear difference in non‐serious adverse eventsClinical manifestation and laboratory… (low certainty).

1 finding from 1 review

Corticosteroids vs placebo compared

Serious adverse events (dichotomous data) ‐ suspected or probable pneumonia · critically ill patients

Corticosteroids showed no clear difference in serious adverse events (dichotomous data) ‐ suspected or probable… compared with placebo compared (high certainty).

1 finding from 1 review

Vaccination vs placebo

Serious adverse events among subjects in the adverse event substudy clinical manifestations · people at risk for postherpetic neuralgia

Vaccination leads to higher serious adverse events among subjects in the adverse event substudy… compared with placebo (high certainty).

1 finding from 1 review