Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

18 questions · 18 findings · 8 reviews

No studies found 2 · 11.1%GRADE not reported 1 · 5.6%Very low 11 · 61.1%Low 3 · 16.7%Moderate 1 · 5.6%High 0 · 0%

Summary of findings: pioglitazone monotherapy vs no intervention

Serious adverse events (N) · people at increased risk for developing type 2 diabetes

Summary of findings: pioglitazone monotherapy showed no clear difference in serious adverse events (N) compared with no intervention (low certainty).

1 finding from 1 review

Oral + inhaled dual therapy vs oral monotherapy

Serious adverse events. Outcome assessed on day 42 · bronchiectasis

It is very uncertain whether oral + inhaled dual therapy changes serious adverse events. Outcome assessed on day 42 compared with oral monotherapy (very low certainty).

1 finding from 1 review