Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Airways

No studies found 2 · 40%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 0 · 0%High 0 · 0%

Serious adverse events · children with bronchiectasis

Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.43 [0.17, 1.05]
1 study · 89 participants
Low

Serious adverse events · adults with bronchiectasis

Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.49 [0.2, 1.23]
3 studies · 326 participants
Low

Serious adverse events (including mortality) · adults and children with chronic asthma

Macrolides showed no clear difference in serious adverse events (including mortality) Weighted mean study… compared with placebo (low certainty).

1 finding from 1 review

Macrolides versus placebo for chronic asthma 2021 · Cochrane Headline outcomes only
OR 0.8 [0.49, 1.31]
8 studies · 854 participants
Low

Serious adverse events ‐ not reported · children with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Serious adverse events ‐ not reported · adults with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found