Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 0 · 0%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Serious adverse events · children with chronic constipation without a physical explanation

1 finding from 1 review

Probiotics for treatment of chronic constipation in children 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 308 participants
GRADE not reported

Serious adverse events · patients aged 0 to 18 years with a diagnosis of functional constipation

PEG showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 0 [0.02, 1.51]
2 studies · 101 participants
Low

Serious adverse events · patients aged 0 to 18 years with a diagnosis of functional constipation

PEG showed no clear difference in serious adverse events compared with lactulose (low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 2 [0.37, 15.96]
2 studies · 145 participants
Low