What do systematic reviews say?

Acarbose vs no intervention

The review found no eligible studies for this question.

• Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: pioglitazone monotherapy vs intensive behaviour‐changing intervention

• Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 103 participants
  Low

Summary of findings: pioglitazone monotherapy vs no intervention

Summary of findings: pioglitazone monotherapy showed no clear difference in serious adverse events (N) compared with no intervention (low certainty).

• Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
  RR 0.71 [0.38, 1.32]
  7 studies · 1211 participants
  Low

Intervention not reported

The intervention showed no clear difference in adverse events (serious adverse events) (low certainty).

• Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
  RR 0.57 [0.17, 1.93]
  31 studies · 4096 participants
  Low

Intervention not reported

The intervention showed no clear difference in adverse events a. Serious adverse events b. Discontinuation of trial… (low certainty).

• Drug interventions for the treatment of obesity in children and adolescents 2016 · Cochrane Headline outcomes only
  RR 1.43 [0.63, 3.25]
  5 studies · 1347 participants
  Low