Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Hepato-Biliary

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Carvedilol vs beta‐blocker

Serious adverse events · adults with cirrhosis and gastroesophageal varices

Carvedilol showed no clear difference in serious adverse events compared with traditional, non‐selective beta‐blockers (low certainty).

1 finding from 1 review

Carvedilol versus traditional, non‐selective beta‐blockers for adults with cirrhosis and gastroesophageal varices 2018 · Cochrane Headline outcomes only
RR 0.97 [0.67, 1.42]
10 studies · 810 participants
Low

Carvedilol vs beta‐blocker

Non‐serious adverse events · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes non‐serious adverse events compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Carvedilol versus traditional, non‐selective beta‐blockers for adults with cirrhosis and gastroesophageal varices 2018 · Cochrane Headline outcomes only
RR 0.55 [0.23, 1.29]
6 studies · 596 participants
Very low