Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Serious adverse events* · adults with renal vasculitis for maintenance therapy

Leflunomide showed no clear difference in serious adverse events* compared with methotrexate (low certainty).

1 finding from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 11.81 [0.69, 203.68]
1 study · 54 participants
Low

Serious adverse events (leflunomide) assessed by number of events · psoriatic arthritis

1 finding from 1 review

Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 61 participants
Very low