Moderate-severe active dental caries (exposure) vs Caries-free or mild dental caries (control)
TNF-α level · Children and young adults (3-25 years)
Salivary TNF-α levels are significantly higher in children and young adults with active dental caries than in caries-free or mild-caries controls (SMD 14.81 pg/mL, 95% CI 4.76 to 24.86; 7 studies); ungraded.
1 finding from 1 review
- Activity and levels of TNF-α, IL-6 and IL-8 in saliva of children and young adults with dental caries: a systematic… 2024 All outcomesObservational studies in children and young adults across nine countries (saliva-based cytokine comparison)SMD 14.81 [4.76, 24.86]7 studies · 348 participantsGRADE not reported