Moderate-severe active dental caries (exposure) vs Caries-free or mild dental caries (control)
Salivary IL-6 level (pg/mL) · Children and young adults (3-25 years)
Salivary IL-6 levels are significantly higher in children and young adults with active dental caries than in caries-free or mild-caries controls (SMD 11.60 pg/mL, 95% CI 6.27 to 16.94; 11 studies); ungraded.
1 finding from 1 review
- Activity and levels of TNF-α, IL-6 and IL-8 in saliva of children and young adults with dental caries: a systematic… 2024 All outcomesObservational studies in children and young adults across nine countries (saliva-based cytokine comparison)SMD 11.60 [6.27, 16.94]11 studies · 879 participantsGRADE not reported