Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · ENT

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No studies found 2 · 66.7%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Antibiotics vs no treatment or placebo on top of topical antibiotics

Resolution of ear discharge ‐ measured after 4 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

It is very uncertain whether systemic antibiotics changes resolution of ear discharge ‐ measured after 4 weeks (6 weeks) (Oral… compared with no treatment or placebo on top of topical antibiotics (very low certainty).

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 1.54 [1.09, 2.16]
1 study · 98 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Resolution of ear discharge ‐ measured after 4 weeks · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found