Findings

What do systematic reviews say?

4 questions · 6 findings · 3 reviews · Airways

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 3 · 50%High 1 · 16.7%

Intramuscular corticosteroids vs oral corticosteroid

Relapse · patients with acute asthma

Intramuscular corticosteroids showed no clear difference in relapse compared with oral corticosteroids (low certainty).

3 findings from 1 review

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.94 [0.72, 1.24]
9 studies · 804 participants
Low
Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.74 [0.51, 1.07]
7 studies · 742 participants
Moderate
Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.99 [0.74, 1.33]
5 studies · 556 participants
Low

Any ICS plus oral corticosteroid vs oral corticosteroid

Asthma relapse1at 20 to 24 days · predominantly adults with acute asthma following emergency department discharge

Any ICS plus oral corticosteroid showed no clear difference in asthma relapse1at 20 to 24 days compared with oral corticosteroid (high certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 0.68 [0.46, 1.02]
3 studies · 909 participants
High

Any ICS vs oral corticosteroid

Asthma relapse1at 16 to 21 days · patients with acute asthma following emergency department discharge

Any ICS showed no clear difference in asthma relapse1at 16 to 21 days compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 1.26 [0.8, 1.99]
2 studies · 425 participants
Moderate

Treatment route: intravenous corticosteroid vs oral corticosteroid

Relapse Hospital readmission for COPD · exacerbations of COPD

Treatment route: intravenous corticosteroid showed no clear difference in relapse Hospital readmission for COPD compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease 2014 · Cochrane Headline outcomes only
OR 0.95 [0.5, 1.8]
3 studies · 298 participants
Moderate