Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Haematology

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Ruxolitinib vs best available therapy

Reduction in spleen size Magnetic resonance imaging or computed tomography · Patients with treating MF

Ruxolitinib may leads to higher reduction in spleen size Magnetic resonance imaging or computed… compared with best available therapy (low certainty).

1 finding from 1 review

Janus kinase‐1 and Janus kinase‐2 inhibitors for treating myelofibrosis 2015 · Cochrane Headline outcomes only
RR 41.78 [2.61, 669.75]
1 study · 219 participants
Low

Ruxolitinib vs placebo

Reduction in spleen size Magnetic resonance imaging or computed tomography · Patients with treating MF

Ruxolitinib may leads to higher reduction in spleen size Magnetic resonance imaging or computed… compared with placebo (low certainty).

1 finding from 1 review

Janus kinase‐1 and Janus kinase‐2 inhibitors for treating myelofibrosis 2015 · Cochrane Headline outcomes only
RR 64.58 [9.08, 459.56]
1 study · 309 participants
Low