Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Gut

Sort:Best matchNewest Highest certainty Download CSV

No studies found 1 · 20%GRADE not reported 0 · 0%Very low 3 · 60%Low 0 · 0%Moderate 1 · 20%High 0 · 0%

Epinephrine vs epinephrine and any second endoscopic method

Recurrent and persistent bleeding overall rates with or without second‐look endoscopy Rebleeding (persistent or recurrent bleeding) · patients with high‐risk bleeding ulcers

Epinephrine probably leads to lower recurrent and persistent bleeding overall rates with or without… compared with epinephrine and any second endoscopic method (moderate certainty).

1 finding from 1 review

Epinephrine injection versus epinephrine injection and a second endoscopic method in high‐risk bleeding ulcers 2014 · Cochrane Headline outcomes only
RR 0.57
19 studies · 1926 participants
Moderate

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

Rebleeding · people with acute UGIH

It is very uncertain whether erythromycin plus nasogastric tube lavage changes rebleeding compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
RR 1.13 [0.63, 2.02]
1 study · 169 participants
Very low

Erythromycin vs nasogastric tube lavage

Rebleeding · people with acute UGIH

It is very uncertain whether erythromycin changes rebleeding compared with nasogastric tube lavage (very low certainty).

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
RR 0.77 [0.4, 1.49]
1 study · 169 participants
Very low

Erythromycin plus nasogastric tube lavage vs metoclopramide plus nasogastric tube lavage

Rebleeding · people with acute UGIH

The review found no eligible studies for this question.

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Erythromycin vs placebo

Rebleeding · people with acute UGIH

It is very uncertain whether erythromycin changes rebleeding compared with placebo (very low certainty).

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
RR 0.63 [0.13, 2.9]
2 studies · 195 participants
Very low