Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

99 questions · 102 findings · 1 reviews · All outcomes

No studies found 0 · 0%GRADE not reported 74 · 72.5%Very low 11 · 10.8%Low 13 · 12.7%Moderate 4 · 3.9%High 0 · 0%

Metapex (calcium hydroxide/iodoform) vs Endoflas chlorophenol free (Endoflas-CF)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with endoflas chlorophenol free (Endoflas-CF); GRADE not reported.

1 finding from 1 review

Calcium hydroxide (CH) vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) probably leads to higher radiological failure compared with formocresol (FC) (moderate certainty).

2 findings from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) may leads to lower radiological failure compared with calcium hydroxide (CH) (low certainty).

2 findings from 1 review

Glutaraldehyde + calcium hydroxide (CH) vs Glutaraldehyde + zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with glutaraldehyde + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Biodentine vs Tempophore

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in radiological failure compared with tempophore; GRADE not reported.

1 finding from 1 review

Glutaraldehyde + calcium hydroxide (CH) vs Full strength formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) vs Calcium hydroxide + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Sealapex (eugenol-free calcium hydroxide) vs Zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Sealapex (eugenol-free calcium hydroxide) showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review