What do systematic reviews say?

ICU follow‐up services vs standard care or no follow‐up service

• Follow‐up services for improving long‐term outcomes in intensive care unit (ICU) survivors 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 286 participants
  Low

Follow‐up integrating additional patient symptom education or monitoring, or survivorship care plans vs usual care

• Follow‐up strategies following completion of primary cancer treatment in adult cancer survivors 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Chemotherapy with TKI followed by TKI maintenance vs chemotherapy alone

• Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 146 participants
  Low

Chemotherapy with TKI followed by TKI maintenance vs chemotherapy alone

• Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1340 participants
  Moderate

Chemotherapy with bevacizumab followed by bevacizumab maintenance vs chemotherapy alone

• Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 486 participants
  Low

Chemotherapy with bevacizumab followed by bevacizumab maintenance vs chemotherapy alone

• Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 890 participants
  High

Low‐intensity pulsed ultrasound vs control

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 393 participants
  Very low

Chemotherapy with TKI (peptide‐Fc fusion protein) followed by TKI maintenance vs chemotherapy alone

The review found no eligible studies for this question.

• Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Low dietary fat vs usual fat

• Effects of total fat intake on body fatness in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40130 participants
  Low

Low‐level laser therapy vs placebo

It is very uncertain whether electromagnetic radiation (low-level laser therapy) changes change in quality of life (QoL) compared with placebo (very low certainty).

• Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes

  short-term (up to 3 months)
  MD -5.24 [-7.38, -3.09]
  1 study · 58 participants
  Very low

Low income vs High family income

Children from low-income families had higher odds of poor OHRQoL (OR 1.16, 95% CI 1.11-1.21; 4 studies; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income country (Brazil); studies 2010-2014
  OR 1.16 [1.11, 1.21]
  4 studies
  GRADE not reported

Low maternal education (<=6 years of schooling) vs Higher maternal education (>6 years)

Lower maternal education was associated with poor OHRQoL (OR 1.12, 95% CI 1.00-1.23; 4 studies; high heterogeneity; CI lower bound at the null; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries; studies 2010-2014
  OR 1.12 [1.00, 1.23]
  4 studies
  GRADE not reported

Dental cavity liner (e.g. calcium hydroxide, glass ionomer, resin-modified glass ionomer, or flowable composite) placed under the restoration vs No cavity liner or a different liner material

No included study reported oral health-related quality of life (a planned outcome), so no evidence is available.

• Efficacy of different cavity liners compared to no cavity lining in managing deep caries in vital permanent teeth - a… 2025 All outcomes

  >=6 months · Dental clinical settings (multiple countries)
  no estimate extracted
  0 studies
  No studies found

Sertraline vs cognitive behavioural therapy

• Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 118 participants
  Moderate

Psychotherapy preceded by motivational interviewing vs psychotherapy alone

• Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 47 participants
  Very low

Exercise vs no treatment

It is very uncertain whether physical exercise changes quality of life VEINES‐QOL/SF‐36/CIVIQ‐20 (lower is better) compared with no treatment (very low certainty).

• Physical exercise for the treatment of non‐ulcerated chronic venous insufficiency 2023 · Cochrane Headline outcomes only
  MD 4.6
  2 studies · 61 participants
  Very low

COMPARISON 1. ARIPIPRAZOLE vs CLOZAPINE

• Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 132 participants
  Very low

Urodynamics vs clinical management (CM)

• Urodynamic studies for management of urinary incontinence in children and adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 75 participants
  Moderate

Acupuncture vs no treatment

The review found no eligible studies for this question.

• Acupuncture for chronic nonspecific low back pain 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Information or education intervention vs no education

• Information or education interventions for adult intensive care unit (ICU) patients and their carers 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 143 participants
  Very low