Findings

What do systematic reviews say?

31 questions · 31 findings · 20 reviews · Headline outcomes only

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No studies found 2 · 6.5%GRADE not reported 1 · 3.2%Very low 11 · 35.5%Low 9 · 29%Moderate 6 · 19.4%High 2 · 6.5%

ICU follow‐up services vs standard care or no follow‐up service

Health‐related quality of life (HRQoL) · adult survivors of the ICU, excluding those already in an existing follow‐up or rehabilitation programme

1 finding from 1 review

Follow‐up services for improving long‐term outcomes in intensive care unit (ICU) survivors 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 286 participants
Low

Follow‐up integrating additional patient symptom education or monitoring, or survivorship care plans vs usual care

Health‐related quality of life (HRQoL) · adult cancer survivors from the following cancer sites: breast, colorectal, endometrial, ovarian and prostate cancer

1 finding from 1 review

Follow‐up strategies following completion of primary cancer treatment in adult cancer survivors 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Low‐intensity pulsed ultrasound vs control

QoL · acute fractures in adults; included studies assessed effects in complete upper limb fractures (distal radius, clavicle, scaphoid,…

1 finding from 1 review

Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 393 participants
Very low

Chemotherapy with TKI followed by TKI maintenance vs chemotherapy alone

QoL · platinum‐sensitive recurrent EOC

1 finding from 1 review

Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Low

Chemotherapy with TKI followed by TKI maintenance vs chemotherapy alone

QoL · newly‐diagnosed EOC

1 finding from 1 review

Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1340 participants
Moderate

Chemotherapy with bevacizumab followed by bevacizumab maintenance vs chemotherapy alone

QoL · platinum‐sensitive recurrent EOC

1 finding from 1 review

Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 486 participants
Low

Chemotherapy with bevacizumab followed by bevacizumab maintenance vs chemotherapy alone

QoL · newly‐diagnosed EOC

1 finding from 1 review

Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 890 participants
High

Chemotherapy with TKI (peptide‐Fc fusion protein) followed by TKI maintenance vs chemotherapy alone

QoL · newly‐diagnosed EOC

The review found no eligible studies for this question.

1 finding from 1 review

Angiogenesis inhibitors for the treatment of epithelial ovarian cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low dietary fat vs usual fat

Potential harms ‐ quality of life (QoL) · Adults (general population)

1 finding from 1 review

Effects of total fat intake on body fatness in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40130 participants
Low

Sertraline vs cognitive behavioural therapy

Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Moderate

Psychotherapy preceded by motivational interviewing vs psychotherapy alone

Quality of life As measured by QOLIE10 (lower is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

1 finding from 1 review

Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 47 participants
Very low

Exercise vs no treatment

QoL · people with non‐ulcerated chronic venous insufficiency

It is very uncertain whether physical exercise changes quality of life VEINES‐QOL/SF‐36/CIVIQ‐20 (lower is better) compared with no treatment (very low certainty).

1 finding from 1 review

Physical exercise for the treatment of non‐ulcerated chronic venous insufficiency 2023 · Cochrane Headline outcomes only
MD 4.6
2 studies · 61 participants
Very low

COMPARISON 1. ARIPIPRAZOLE vs CLOZAPINE

QoL · patients with schizophrenia

1 finding from 1 review

Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 132 participants
Very low

Urodynamics vs clinical management (CM)

Health status and quality of life · patients with management of urinary incontinence in children and adults

1 finding from 1 review

Urodynamic studies for management of urinary incontinence in children and adults 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 75 participants
Moderate

Acupuncture vs no treatment

Potential harms ‐ quality of life (QoL) · patients with non‐specific chronic low back pain

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for chronic nonspecific low back pain 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Information or education intervention vs no education

Health‐related quality of life (HRQoL) · adult ICU patients and their carers

1 finding from 1 review

Information or education interventions for adult intensive care unit (ICU) patients and their carers 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 143 participants
Very low

Summary of findings (water exercise vs no exercise

Quality of life St George's Respiratory Questionnaire (SGRQ) score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Water‐based exercise training for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
no estimate extracted
19 participants
Low

Summary of findings (water exercise vs land exercise)

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Water‐based exercise training for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
no estimate extracted
60 participants
Low

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Serenoa repens vs placebo or no intervention

QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Serenoa repens showed no clear difference in quality of lifeMeasured by IPSS‐QoL score (range 0 to 6) compared with placebo or no intervention (high certainty).

1 finding from 1 review

Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1001 participants
High