Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

23 questions · 24 findings · 8 reviews · Headline outcomes only

No studies found 11 · 45.8%GRADE not reported 1 · 4.2%Very low 9 · 37.5%Low 1 · 4.2%Moderate 2 · 8.3%High 0 · 0%

Targeted immunotherapy alone vs standard targeted therapies

Quality of life: improved to an important degree · previously treated patients with mRCC

Targeted immunotherapy alone probably leads to higher quality of life: Clinically relevant improvement in FKSI‐DRS compared with standard targeted therapies (moderate certainty).

2 findings from 1 review