Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 4 reviews · Oral medicine and oral cancer

No studies found 3 · 60%GRADE not reported 2 · 40%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Patient quality of life · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Chemotherapy (any regimen; added to, or compared with, locoregional treatment) vs Locoregional treatment and/or an alternative chemotherapy regimen

Quality of life · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

The review found no eligible studies for this question.

1 finding from 1 review

Commercial mouthcare system (Biotene Oral Balance / Xerostom) vs Bioxtra mouthcare system

Quality of life (xerostomia-related) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
  • No difference between systems for overall xerostomia-related quality of life (15-item survey). Bioxtra rated better for taste; no difference for mouth 'feel'. Trial likely underpowered.
    1 study · 20 participants
    GRADE not reported