What do systematic reviews say?

Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo

It is very uncertain whether arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement changes quality of life compared with placebo (very low certainty).

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 270 participants
  Very low

Laxative plus bulking agent vs laxative alone

The review found no eligible studies for this question.

• Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Laxative vs placebo

The review found no eligible studies for this question.

• Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CBT with therapist support vs fatigue information leaflet only

• Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 19 participants
  Very low

Electroacupuncture vs no treatment

• Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 27 participants
  Low

Physical activity advice plus omega 3 vs no physical activity advice plus omega 3

• Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Electroacupuncture vs sham electroacupuncture

• Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Low

Long‐term red cell transfusion vs usual care

• Interventions for preventing silent cerebral infarcts in people with sickle cell disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 196 participants
  Low

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: Beta‐blockers vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

ACUTE: Serelaxin vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning

The review found no eligible studies for this question.

• Interventions for managing halitosis 2019 · Cochrane All outcomes
  Quality of life was a prespecified secondary outcome. None of the 44 included studies in the review (across all comparisons) reported quality-of-life data (review-wide evidence gap).
  0 studies
  No studies found

Clinic‐based intervention vs usual care

• Disease management interventions for heart failure 2019 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 641 participants
  Low

Sodium thiosulfate vs no otoprotective intervention

The review found no eligible studies for this question.

• Medical interventions for the prevention of platinum‐induced hearing loss in children with cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Amifostine vs no otoprotective intervention

The review found no eligible studies for this question.

• Medical interventions for the prevention of platinum‐induced hearing loss in children with cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Biotin vs placebo

The review found no eligible studies for this question.

• Interventions for infantile seborrhoeic dermatitis (including cradle cap) 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Proprietary products vs placebo

The review found no eligible studies for this question.

• Interventions for infantile seborrhoeic dermatitis (including cradle cap) 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical steroid vs comparator

The review found no eligible studies for this question.

• Interventions for infantile seborrhoeic dermatitis (including cradle cap) 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs non‐surgical treatment

The review found no eligible studies for this question.

• Surgical interventions for symptomatic mild to moderate knee osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found