Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

131 questions · 131 findings · 33 reviews

No studies found 93 · 71%GRADE not reported 8 · 6.1%Very low 17 · 13%Low 8 · 6.1%Moderate 4 · 3.1%High 1 · 0.8%

Selenium vs no intervention

Quality of life and other oral related symptoms (loss of taste, dysphagia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review

Surgery vs Pharmacological therapy

Health‐related quality of life Mean AcroQoL score (0‐100) · adults with growth‐hormone secreting pituitary adenomas

Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).

1 finding from 1 review