What do systematic reviews say?

Ball (stud) attachment system vs Magnetic attachment system

• Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws 2018 · Cochrane All outcomes
  Two trials (Cune 2010; Naert 1999) reported patient satisfaction. However, we could not use any data from these studies. Quality of life as assessed by a validated measure was not recorded in any of the trials.
  2 studies
  GRADE not reported

Surgical vs non‐surgical treatment

Surgical showed no clear difference in quality of life: EQ‐5D (0: dead to 1: best quality of life) compared with non‐surgical treatment (high certainty).

• Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes only
  MD 0.01
  6 studies · 502 participants
  High

Reverse total shoulder arthroplasty (RTSA) vs hemiarthroplasty

• Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 83 participants
  Very low

Early vs delayed mobilisation

• Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 39 participants
  Very low

Summary of findings ‐ Interactive Social Media vs non‐interactive social media

• Behavioural interventions delivered through interactive social media for health behaviour change, health outcomes, and… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  16 studies · 3792 participants
  Low

Erythrocytapheresis vs phlebotomy

• Interventions for hereditary haemochromatosis 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 38 participants
  Very low

Intervention not reported

• Interventions to change the behaviour of health professionals and the organisation of care to promote weight reduction… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 96 participants
  Low

Intervention not reported

• Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 71 participants
  Very low

Omega‐3 vs placebo

• Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Group A: amino acids vs placebo

• Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Cognitive training vs active control

• Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Group C other: family treatment vs enhanced care

• Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Group C other: integrated treatment vs usual care

• Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 972 participants
  Low

Amifostine vs no treatment/placebo

It is very uncertain whether amifostine changes quality of life (Patient Benefit Questionnaire, 10-point scale) compared with no treatment/placebo (very low certainty).

• Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes

  12 months postRT
  MD 0.70 [0.20, 1.20]
  1 study · 180 participants
  Very low

Physical exercise training vs usual care

• Physical exercise training interventions for children and young adults during and after treatment for childhood cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 28 participants
  Low

Flutamide 250 mg once to b.i.d. vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Spironolactone 100 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg to 7.5 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found