Findings

What do systematic reviews say?

701 questions · 713 findings · 246 reviews

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No studies found 398 · 55.8%GRADE not reported 59 · 8.3%Very low 114 · 16%Low 98 · 13.7%Moderate 40 · 5.6%High 4 · 0.6%

Smartphone app vs no intervention or minimal intervention

Health‐related quality of life(WHOQOL‐BREF questionnaire, score · adults

1 finding from 1 review

Mobile health (m‐health) smartphone interventions for adolescents and adults with overweight or obesity 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 149 participants
Moderate

Omega‐3 vs placebo

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Group B antipsychotic drugs: amisulpiride + needs‐focused intervention vs needs‐focused intervention

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Group A: amino acids vs placebo

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Group C cognitive behavioural therapy: cognitive behavioural therapy + supportive intervention vs non‐directive reflective listening + supportive intervention

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Cognitive training vs active control

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Group C other: family treatment vs enhanced care

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Group C other: integrated treatment vs usual care

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Health‐related quality of life Validated self‐reported measures · adolescents (aged 12‐17 years) being overweight or obese

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 972 participants
Low

Amifostine vs no treatment/placebo

Quality of life (Patient Benefit Questionnaire, 10-point scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

It is very uncertain whether amifostine changes quality of life (Patient Benefit Questionnaire, 10-point scale) compared with no treatment/placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes
12 months postRT
MD 0.70 [0.20, 1.20]
1 study · 180 participants
Very low

Flutamide 250 mg once to b.i.d. vs spironolactone 100 mg

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

Change in health‐related quality of life (HRQOL) ‐ not measured · patients with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Spironolactone 100 mg vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Finasteride 5 mg to 7.5 mg vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Finasteride 5 mg vs spironolactone 100 mg

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Flutamide 250 mg b.i.d. vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Porter 2020: armodafinil vs placebo

Quality of life, self‐rated at post‐treatment · people with a primary brain tumour

1 finding from 1 review

Interventions for the management of fatigue in adults with a primary brain tumour 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 232 participants
Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Quality of life / life satisfaction: Brief Quality of Life Scale · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 110 participants
Low