Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

725 questions · 738 findings · 261 reviews

No studies found 403 · 54.6%GRADE not reported 61 · 8.3%Very low 124 · 16.8%Low 101 · 13.7%Moderate 45 · 6.1%High 4 · 0.5%

Amifostine vs no treatment/placebo

Quality of life (Patient Benefit Questionnaire, 10-point scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

It is very uncertain whether amifostine changes quality of life (Patient Benefit Questionnaire, 10-point scale) compared with no treatment/placebo (very low certainty).

1 finding from 1 review