Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 29 findings · 20 reviews

No studies found 8 · 27.6%GRADE not reported 2 · 6.9%Very low 10 · 34.5%Low 6 · 20.7%Moderate 3 · 10.3%High 0 · 0%

Fixed‐dose combination aclidinium/formoterol vs aclidinium alone

Quality of life: number of participants with clinically significant improvement (≥ 4 units) in SGRQ total score · patients with chronic obstructive pulmonary disease

Fixed‐dose combination aclidinium/formoterol showed no clear difference in quality of life: number of participants with clinically significant… compared with aclidinium alone (moderate certainty).

1 finding from 1 review