Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Neonatal

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No studies found 2 · 40%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 1 · 20%High 0 · 0%

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Pulmonary hemorrhage · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in pulmonary hemorrhage compared with modified bovine minced lung surfactant extract (moderate certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 1.08 [0.74, 1.59]
4 studies · 2138 participants
Moderate

Bovine lung lavage surfactant extract vs porcine minced lung surfactant extract

Pulmonary hemorrhage · Preterm infants for treatment of RDS

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified bovine minced lung surfactant extract vs porcine minced lung surfactant extract

Pulmonary hemorrhage · Preterm infants for treatment of RDS

Modified bovine minced lung surfactant extract showed no clear difference in pulmonary hemorrhage compared with porcine minced lung surfactant extract (low certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 1.28 [0.81, 2.02]
8 studies · 871 participants
Low

Modified bovine minced lung surfactant extract vs porcine lung lavage surfactant

Pulmonary hemorrhage · Preterm infants for treatment of RDS

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Pulmonary hemorrhage · Preterm infants for prevention of RDS

Bovine lung lavage surfactant extract showed no clear difference in pulmonary hemorrhage compared with modified bovine minced lung surfactant extract (low certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 1.44 [0.88, 2.39]
2 studies · 1123 participants
Low