Findings

What do systematic reviews say?

12 questions · 12 findings · 1 reviews · Pain, Palliative and Supportive Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 33.3%Low 6 · 50%Moderate 1 · 8.3%High 1 · 8.3%

Summary of findings table ‐ GABA‐analogues vs placebo

Pruritus · health problem or population

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 297 participants
Moderate

Summary of findings table ‐ Kappa‐opioid agonists vs placebo

Pruritus · patients with chronic kidney disease (CKD) pruritus

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1292 participants
High

Summary of findings table ‐ Ondansetron vs placebo

Pruritus · patients with chronic kidney disease (CKD) pruritus

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 202 participants
Low

Montelukast vs placebo

Pruritus · patients with chronic kidney disease (CKD) pruritus

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 87 participants
Very low

Zinc sulphate vs placebo

Pruritus · patients with chronic kidney disease (CKD) pruritus

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Low

Cromolyn sodium vs placebo

Pruritus · patients with chronic kidney disease (CKD) pruritus

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 100 participants
Very low

Summary of findings table ‐ Topical capsaicin vs placebo

Pruritus · patients with chronic kidney disease (CKD) pruritus

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 112 participants
Low

Summary of findings table ‐ Rifampin/rifampicin vs placebo

Pruritus · participants with cholestatic pruritus (CP)

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 42 participants
Very low

Flumecinol vs placebo

Pruritus · participants with cholestatic pruritus (CP)

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Gabapentin vs pregabalin

Pruritus · patients with chronic kidney disease (CKD) pruritus

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 100 participants
Low

naltrexone vs placebo

PruritusScale from: 0 to 10 · participants with cholestatic pruritus (CP)

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 52 participants
Low

Flumecinol vs placebo

Pruritus: significant improvement · participants with cholestatic pruritus (CP)

It is very uncertain whether summary of findings table ‐ Flumecinol changes pruritus: significant improvement compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
RR 2.32 [0.54, 10.1]
2 studies · 69 participants
Very low