Findings

What do systematic reviews say?

3 questions · 4 findings · 1 reviews · ENT

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 1 · 25%Moderate 1 · 25%High 0 · 0%

Intratympanic corticosteroids vs systemic corticosteroids

Proportion of patients whose hearing is improved · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in proportion of patients whose hearing is improved compared with systemic corticosteroids (moderate certainty).

1 finding from 1 review

Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes only
RR 1.04 [0.97, 1.12]
14 studies · 972 participants
Moderate

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Proportion of patients whose hearing is improved · sudden sensorineural hearing loss

It is very uncertain whether intratympanic plus systemic corticosteroids (combined therapy) changes proportion of patients whose hearing is improved compared with systemic corticosteroids alone (very low certainty).

2 findings from 1 review

Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes only
RR 1.27 [1.15, 1.41]
10 studies · 788 participants
Very low
Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes only
RR 2.24 [1.1, 4.55]
1 study · 76 participants
Very low

Intratympanic corticosteroids vs no treatment or versus placebo

Proportion of patients whose hearing is improved · sudden sensorineural hearing loss

Intratympanic corticosteroids may leads to higher proportion of patients whose hearing is improved compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes only
RR 5.55 [2.89, 10.68]
6 studies · 232 participants
Low