Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Neonatal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Higher dose vitamin K vs lower dose vitamin K

Presence of PIVKA II at day 5: 0.2 mg IM versus 0.5 mg IM · preterm infants

Higher dose vitamin K showed no clear difference in presence of PIVKA II at day 5: 0.2 mg IM versus 0.5 mg IM compared with lower dose vitamin K (low certainty).

1 finding from 1 review

Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates 2018 · Cochrane Headline outcomes only
RR 1.36 [0.24, 7.57]
1 study · 61 participants
Low

Higher dose vitamin K vs lower dose vitamin K

Presence of PIVKA II at day 25: 0.2 mg IM versus 0.5 mg IM · preterm infants

Higher dose vitamin K showed no clear difference in presence of PIVKA II at day 25: 0.2 mg IM versus 0.5 mg IM compared with lower dose vitamin K (low certainty).

1 finding from 1 review

Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates 2018 · Cochrane Headline outcomes only
RR 0.96 [0.06, 14.6]
1 study · 53 participants
Low