What do systematic reviews say?

Monoclonal antibody vs polyclonal antibody

Monoclonal antibody showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with polyclonal antibody (low certainty).

• Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
  RR 3.84 [0.45, 32.96]
  4 studies · 157 participants
  Low

Interleukin‐2 RA induction vs monoclonal antibody induction

Interleukin‐2 RA induction showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with monoclonal antibody induction (low certainty).

• Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
  RR 0.31 [0.01, 7.38]
  2 studies · 159 participants
  Low

Interleukin‐2 RA vs polyclonal antibody induction

• Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 185 participants
  Low

Interleukin‐2 RA vs no induction

Interleukin‐2 RA showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with no induction (low certainty).

• Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
  RR 0.61 [0.08, 4.92]
  4 studies · 576 participants
  Low

Intervention not reported

The intervention showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… (low certainty).

• Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
  RR 0.74 [0.14, 3.82]
  5 studies · 606 participants
  Low