Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Neonatal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

HFNC vs nasal intermittent positive pressure ventilation

Pneumothorax · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in pneumothorax (during assigned treatment) compared with nasal intermittent positive pressure ventilation (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.78 [0.4, 1.53]
4 studies · 344 participants
Moderate

HFNC vs continuous positive airway pressure (CPAP)

Pneumothorax · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in pneumothorax (during assigned treatment) compared with continuous positive airway pressure (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.66 [0.4, 1.08]
10 studies · 2094 participants
Moderate