Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Kidney and Transplant

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 80%Low 1 · 20%Moderate 0 · 0%High 0 · 0%

10‐day trimethoprim vs 10‐day trimethoprim+sulfamethoxazole

Persistent symptoms · children with lower urinary tract infection

It is very uncertain whether 10‐day trimethoprim changes persistent symptoms compared with 10‐day trimethoprim+sulfamethoxazole (very low certainty).

1 finding from 1 review

Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
RR 4.84 [0.24, 96.66]
1 study · 59 participants
Very low

10‐day cefadroxil vs 10‐day ampicillin

Persistent symptoms · children with lower urinary tract infection

It is very uncertain whether 10‐day cefadroxil changes persistent symptoms compared with 10‐day ampicillin (very low certainty).

1 finding from 1 review

Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
RR 0.33 [0.01, 7.62]
1 study · 32 participants
Very low

Single‐dose vs 10 days

Persistent symptoms · children with lower urinary tract infection

It is very uncertain whether single‐dose changes persistent symptoms compared with conventional 10‐day antibiotic treatment (very low certainty).

1 finding from 1 review

Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
RR 0.29 [0.03, 2.5]
1 study · 30 participants
Very low

Single‐dose vs 10 days

Persistent bacteriuria and symptoms · children with lower urinary tract infection

It is very uncertain whether single‐dose changes persistent bacteriuria and symptoms compared with conventional 10‐day antibiotic treatment (very low certainty).

1 finding from 1 review

Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
RR 1.83 [0.18, 18.84]
1 study · 46 participants
Very low

Third generation cephalosporins vs other antibiotics

Persistent symptoms · children with acute pyelonephritis

Agent: Third generation cephalosporin may leads to lower persistent symptoms after end of treatment compared with other antibiotic (low certainty).

1 finding from 1 review

Antibiotics for acute pyelonephritis in children 2014 · Cochrane Headline outcomes only
RR 0.28 [0.13, 0.62]
3 studies · 471 participants
Low