Evidence Gaps

Periapical pathosis incidence · Vital teeth

The pooled incidence with > 5–10 years of follow-up was 3.88%.

1 finding from 1 review

Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes
> 5–10 years · > 5–10 years
Proportion 3.88 [1.95, 6.45]
1864 participants
GRADE not reported

Periapical pathosis · Vital teeth restored with indirect restorations

Periapical pathosis incidence among follow-up >5-10 years was 3.88% (subgroup analysis; not GRADE-rated).

6 findings from 1 review

Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes
>5-10 years · University clinics and dental practices, multiple countries · Follow-up >5-10 years
Proportion 3.88 [1.95, 6.45]
1864 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes
>10 years · University clinics and dental practices, multiple countries · Follow-up >10 years
Proportion 4.05 [0.89, 9.36]
2656 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes
Follow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Fixed partial dentures (FPD)
Proportion 4.59 [2.28, 7.64]
9 studies · 2435 participants
GRADE not reported

Show 3 more findings

Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes
Follow-up ≤5 to >10 years · University clinics and dental practices, multiple countries
Proportion 3.63 [2.05, 5.63]
15 studies · 5376 participants
Low
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes
≤5 years · University clinics and dental practices, multiple countries · Follow-up ≤5 years
Proportion 2.26 [0.59, 4.98]
856 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes
Follow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Single-unit restorations
Proportion 2.20 [1.12, 3.61]
6 studies · 2339 participants
GRADE not reported

Periapical pathosis incidence · Vital teeth

One study reported a 1.4% incidence with bone level < 35%.

2 findings from 1 review

What do systematic reviews say?