Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 10 findings · 1 reviews · Headline outcomes only

No studies found 7 · 70%GRADE not reported 0 · 0%Very low 2 · 20%Low 1 · 10%Moderate 0 · 0%High 0 · 0%

Potassium paraaminobenzoate vs placebo

Patient‐reported ability to have intercourse · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

Potassium paraaminobenzoate showed no clear difference in patient‐reported ability to have intercourse compared with placebo (low certainty).

1 finding from 1 review

Injectional collagenase vs placebo

Patient‐reported ability to have intercourse · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)

The review found no eligible studies for this question.

2 findings from 1 review

Injectional verapamil vs saline (short‐term)

Patient‐reported ability to have intercourse · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether injectional verapamil changes patient‐reported ability to have intercourse compared with saline (short‐term) (very low certainty).

1 finding from 1 review

Extracorporeal shockwave therapy vs sham

Patient‐reported ability to have intercourse · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes patient‐reported ability to have intercourse compared with sham (very low certainty).

1 finding from 1 review