Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Topical clonidine (TC) vs active comparators

Number of participants reporting an adverse event · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical clonidine (TC) vs placebo

Number of participants reporting an adverse event · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in participants experiencing at least 1adverse event during longest compared with placebo (low certainty).

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
RR 0.65 [0.14, 3.05]
2 studies · 344 participants
Low