Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Oral medicine and oral cancer

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No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 4 · 66.7%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%

Topical corticosteroids vs placebo

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical corticosteroid may leads to higher pain resolution compared with placebo (low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
8-9 weeks
RR 1.91 [1.08, 3.36]
2 studies · 72 participants
Low

Topical clobetasol propionate vs Topical ciclosporin

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical clobetasol propionate changes pain resolution compared with topical ciclosporin (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
3-8 weeks
RR 2.11 [0.76, 5.86]
1 study · 39 participants
Very low

Dexamethasone ointment vs Amlexanox paste

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether dexamethasone ointment changes pain resolution compared with amlexanox paste (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
RR 0.75 [0.34, 1.66]
1 study · 36 participants
Very low

Topical triamcinolone acetonide vs Topical tacrolimus

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
3-8 weeks
Summary of findings 2: 'No data for this outcome' (triamcinolone vs tacrolimus, pain resolution)
0 studies
No studies found

Topical clobetasol propionate vs Topical tacrolimus

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical clobetasol propionate changes pain resolution compared with topical tacrolimus (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
3-8 weeks
RR 0.45 [0.24, 0.88]
2 studies · 100 participants
Very low

Systemic (oral) betamethasone vs Topical triamcinolone acetonide paste

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether systemic (oral) betamethasone changes pain resolution compared with topical triamcinolone acetonide paste (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
RR 1.04 [0.60, 1.80]
1 study · 49 participants
Very low