Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Pain at 12 hours · patients with postoperative pain

It is very uncertain whether transdermal or intranasal nicotine changes pain at 12 hours compared with placebo (very low certainty).

1 finding from 1 review

Intranasal or transdermal nicotine for the treatment of postoperative pain 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 175 participants
Very low

Pain at 24 hours · patients with postoperative pain

Transdermal or intranasal nicotine showed no clear difference in pain at 24 hours compared with placebo (low certainty).

1 finding from 1 review

Intranasal or transdermal nicotine for the treatment of postoperative pain 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 562 participants
Low