Pain ‐ Pain at 11 to 14 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 11 to 14 days compared with expectant observation (low certainty).
1 finding from 1 review
Pain ‐ pain at 2 to 3 days · children with acute otitis media
Antibiotics leads to lower pain ‐ pain at 2 to 3 days compared with placebo (high certainty).
1 finding from 1 review
Pain ‐ pain at 4 to 7 days · children with acute otitis media
Antibiotics showed no clear difference in pain ‐ pain at 4 to 7 days compared with placebo (high certainty).
1 finding from 1 review
Pain ‐ pain at 10 to 12 days · children with acute otitis media
Antibiotics probably leads to lower pain ‐ pain at 10 to 12 days compared with placebo (moderate certainty).
1 finding from 1 review
Pain ‐ pain at 2 to 3 days · children with acute otitis media
Immediate antibiotics may leads to lower pain ‐ Pain at 2 to 3 days compared with expectant observation (low certainty).
1 finding from 1 review
Pain ‐ Pain at 3 to 7 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 3 to 7 days compared with expectant observation (moderate certainty).
1 finding from 1 review
Little or no pain at 1 to 3 days · people with acute soft tissue injury, such as ankle sprain
It is very uncertain whether NSAID changes little or no pain at 1 to 3 days compared with combination (paracetamol and opioid) analgesic (very low certainty).
1 finding from 1 review
Pain during the first 7 days (VAS means) · adolescent and adult male circumcisions
1 finding from 1 review
Frequency of crisis (number of pain days) · sickle cell disease
N‐acetylcysteine (1200 mg) showed no clear difference in frequency of crisis (number of pain days) compared with placebo (low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · acute soft tissue injury
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with acute soft tissue injury, such as ankle sprain
1 finding from 1 review
Early postoperative pain (VAS 0 ‐ 100, 2 days) · People needing incisional hernia repair
1 finding from 1 review
Early postoperative pain (VAS 0 ‐ 100, 2 days) · People with primary ventral or incisional hernia repair
1 finding from 1 review
no estimate extracted
50 participants
Low
Early postoperative pain (VAS 0 ‐ 100, 2 days) · People with primary ventral or incisional hernia repair
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · sickle cell disease
N‐acetylcysteine (1200 mg) showed no clear difference in severity of pain (maximum pain intensity on pain days) compared with placebo (low certainty).
1 finding from 1 review
Early postoperative pain (VAS 0 ‐ 10, sum 0 to 3 days) · People with primary ventral or incisional hernia repair
1 finding from 1 review
Intervention not reported
Complications of surgery (haemorrhage and days with pain) · children with PFAPA
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain scores, measured in various ways at a median of 2 days' · participants requiring aortic valve replacement
1 finding from 1 review
Abdominal pain frequency or change in frequency · adults and children with cystic fibrosis
It is very uncertain whether summary of findings: ECM changes frequency of bowel symptoms: abdominal pain (% of days affected) compared with ECT (very low certainty).
1 finding from 1 review
Abdominal pain frequency or change in frequency · adults with cystic fibrosis
It is very uncertain whether summary of findings: ECM changes frequency in bowel symptoms: abdominal pain (% of days affected) compared with NECT plus cimetidine (very low certainty).
1 finding from 1 review