Findings

What do systematic reviews say?

Ignored "PE": search terms need at least 3 characters.

3 questions · 3 findings · 1 reviews · Neonatal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Intraventricular haemorrhage · preterm infants at risk of intraventricular haemorrhage

It is very uncertain whether heparin changes any Intraventricular Haemorrage (IVH) compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Heparin for the prevention of intraventricular haemorrhage in preterm infants 2016 · Cochrane Headline outcomes only
RR 0.93 [0.61, 1.41]
2 studies · 155 participants
Very low

Severe intraventricular haemorrhage · preterm infants at risk of intraventricular haemorrhage

Heparin showed no clear difference in severe IVH compared with placebo/no treatment (low certainty).

1 finding from 1 review

Heparin for the prevention of intraventricular haemorrhage in preterm infants 2016 · Cochrane Headline outcomes only
RR 1.01 [0.46, 2.23]
2 studies · 155 participants
Low

Neonatal mortality · preterm infants at risk of intraventricular haemorrhage

Heparin showed no clear difference in neonatal mortality (all‐cause) compared with placebo/no treatment (low certainty).

1 finding from 1 review

Heparin for the prevention of intraventricular haemorrhage in preterm infants 2016 · Cochrane Headline outcomes only
RR 0.69 [0.28, 1.67]
2 studies · 155 participants
Low