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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews · Gynaecology and Fertility

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Metformin combined with clomiphene citrate vs clomiphene

Ovulation rate · women with polycystic ovary syndrome

Metformin combined with clomiphene citrate probably leads to higher ovulation rate per woman compared with clomiphene citrate alone (moderate certainty).

1 finding from 1 review · compare the 2 reviews

Metformin vs clomiphene

Ovulation rate per woman fParticipants with BMI < 30 kg/m2 · women with polycystic ovary syndrome

Metformin showed no clear difference in ovulation rate per woman Participants with BMI < 30 kg/m2b compared with clomiphene citrate (low certainty).

1 finding from 1 review · compare the 2 reviews

Metformin vs clomiphene

Ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome

Metformin may leads to lower ovulation rate per woman Participants with BMI ≥ 30 kg/m2b compared with clomiphene citrate (low certainty).

1 finding from 1 review · compare the 2 reviews