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What do systematic reviews say?

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Evidence found and GRADE certainty

1 questions · 1 findings · 1 reviews · Common Mental Disorders

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Amitriptyline vs placebo

Adverse effects (drop‐outs due to adverse effects4) · adults with Major Depressive Disorder

Amitriptyline probably leads to higher overall tolerability Drop‐out due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review