Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Breast Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Overall survival: Median length of · people with metastatic breast cancer

Capecitabine‐containing regimens showed no clear difference in overall survival (OS)median compared with chemotherapy regimens without capecitabine (high certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
HR 1.01 [0.98, 1.05]
12 studies · 4325 participants
High

Capecitabine‐containing regimens vs non‐capecitabine‐containing regimens or no chemotherapy

Overall survival: Median length of · patients with early breast cancer

Capecitabine‐containing regimens probably leads to lower overall survival (OS)median compared with non‐capecitabine‐containing regimens or no chemotherapy (moderate certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
HR 0.89 [0.81, 0.98]
8 studies · 13547 participants
Moderate