Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Colorectal

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No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

IRI with fluoropyrimidines vs single agent IRI

Overall survival (Death) · patients with advanced and/or metastatic colorectal cancer

IRI with fluoropyrimidines showed no clear difference in overall survival (Death) compared with single agent IRI (low certainty).

1 finding from 1 review

Irinotecan chemotherapy combined with fluoropyrimidines versus irinotecan alone for overall survival and… 2016 · Cochrane Headline outcomes only
HR 0.91 [0.81, 1.02]
5 studies · 1728 participants
Low

Physical activity vs usual care

Overall survival (time interval between enrolment in the study and death of the person from any cause) · adults with non‐advanced colorectal cancer treated surgically or with neoadjuvant or adjuvant therapy, or both

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity interventions for disease‐related physical and mental health during and following treatment in… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found