Docetaxel vs non‐docetaxel‐containing regimens
Docetaxel leads to lower overall survival compared with non‐docetaxel‐containing regimens (high certainty).
- HR 0.86 [0.78, 0.95]8 studies · 2001 participantsHigh
Docetaxel leads to lower overall survival compared with non‐docetaxel‐containing regimens (high certainty).
It is very uncertain whether docetaxel changes overall survival ‐ Other comparisons compared with non‐docetaxel‐containing regimens (very low certainty).
Docetaxel probably leads to lower overall survival ‐ Additive comparisons compared with non‐docetaxel‐containing regimens (moderate certainty).
Docetaxel showed no clear difference in overall survival ‐ Substitutive comparisons compared with non‐docetaxel‐containing regimens (moderate certainty).
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction cisplatin + 5-fluorouracil + docetaxel… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).