Anti‐cancer therapy vs best supportive care
Anti‐cancer therapy showed no clear difference in overall survival compared with best supportive care (moderate certainty).
- HR 1.08 [0.88, 1.33]4 studies · 298 participantsModerate
Anti‐cancer therapy showed no clear difference in overall survival compared with best supportive care (moderate certainty).
Fluoropyrimidine combinations showed no clear difference in overall survival compared with fluoropyrimidine alone (low certainty).
Summary of findings table (subcomparison 4): targeted therapy agent… leads to lower overall survival compared with control intervention alone (high certainty).
5‐FU/cisplatin/anthracycline combinations may leads to lower overall survival compared with 5‐FU/anthracycline combinations (without cisplatin) (low certainty).
Irinotecan probably leads to lower overall survival compared with non‐irinotecan‐containing regimens (moderate certainty).
Docetaxel leads to lower overall survival compared with non‐docetaxel‐containing regimens (high certainty).
Capecitabine showed no clear difference in overall Survival compared with 5‐FU‐containing regimens (moderate certainty).
Oxaliplatin may leads to lower overall Survival compared with the same regimen including cisplatin (low certainty).
It is very uncertain whether taxane‐platinum‐fluoropyrimidine combinations changes overall survival compared with taxane‐platinum (without fluoropyrimidine) (very low certainty).
S‐1 showed no clear difference in overall Survival compared with 5‐FU‐containing regimens (high certainty).
5‐FU/cisplatin/anthracycline combinations probably leads to lower overall survival compared with 5‐FU/cisplatin combinations (without anthracyclines) (moderate certainty).
The intervention showed no clear difference in overall survival (high certainty).
The intervention leads to lower overall survival (high certainty).
Non‐platinum single‐agent may leads to lower overall survival (OS) compared with non‐platinum combination treatment (low certainty).
Non‐platinum therapies probably leads to lower overall survival compared with platinum combination (moderate certainty).
The intervention leads to lower overall survival1 (high certainty).
The intervention showed no clear difference in overall survival (moderate certainty).
It is very uncertain whether hysterectomy (simple or radical) with chemoradiotherapy changes overall survival Median compared with chemoradiotherapy alone (very low certainty).
Hysterectomy (simple or radical) with chemoradiotherapy showed no clear difference in overall survival Median compared with internal radiotherapy (brachytherapy) with chemoradiotherapy (low certainty).
Hysterectomy (simple or radical) with radiotherapy showed no clear difference in overall survival Median compared with radiotherapy alone (low certainty).