Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Oral and maxillofacial surgery

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No studies found 0 · 0%GRADE not reported 1 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Cleft lip and/or palate (CL/P) vs Healthy controls without cleft

Oral microbiota composition · Individuals assessed for oral microbiota (mainly children and adolescents)

Oral microbiota composition differs between persons with orofacial cleft and healthy controls, synthesized qualitatively across 8 studies but not meta-analyzed (ungraded).

1 finding from 1 review

Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and… 2025 All outcomes
Clinical oral/salivary microbial sampling; various countries
no estimate extracted
8 studies
GRADE not reported