Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 5 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Silver diamine fluoride (SDF) vs placebo

Oral health-related quality of life · Children with dental caries

SDF did not significantly differ from placebo for oral health-related quality of life in children (MD 0.03, 95% CI -0.16 to 0.22; ungraded).

1 finding from 1 review

Silver diamine fluoride and oral health-related quality of life: A review and network meta-analysis. 2022 All outcomes
Post-treatment · Pediatric dental care; trials conducted in China, the USA, and Brazil
MD 0.03 [-0.16, 0.22]
2 studies · 440 participants
GRADE not reported

Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART)

Oral health-related quality of life · Children with dental caries

SDF did not significantly differ from atraumatic restorative treatment for oral health-related quality of life (MD 0.02, 95% CI -0.32 to 0.36; ungraded).

1 finding from 1 review

Silver diamine fluoride and oral health-related quality of life: A review and network meta-analysis. 2022 All outcomes
Post-treatment · Pediatric dental care; trials conducted in China, the USA, and Brazil
MD 0.02 [-0.32, 0.36]
2 studies · 134 participants
GRADE not reported

Silver diamine fluoride (SDF) plus fluoride varnish vs Atraumatic restorative treatment + fluoride varnish (ART+FV)

Oral health-related quality of life · Children with dental caries

SDF plus fluoride varnish did not significantly differ from ART plus fluoride varnish for oral health-related quality of life (MD 0.16, 95% CI -0.1 to 0.42; ungraded).

1 finding from 1 review

Silver diamine fluoride and oral health-related quality of life: A review and network meta-analysis. 2022 All outcomes
Post-treatment · Pediatric dental care; trials conducted in China, the USA, and Brazil
MD 0.16 [-0.1, 0.42]
1 study · 246 participants
GRADE not reported

Silver diamine fluoride (SDF, including SDF + fluoride varnish) vs Other standard-of-care caries treatments pooled (placebo, ART, or ART + fluoride varnish)

Oral health-related quality of life · Children with dental caries

SDF had no significant effect on oral health-related quality of life versus pooled standard-of-care caries treatments (SMD -0.06, 95% CI -0.20 to 0.08; ungraded).

1 finding from 1 review

Silver diamine fluoride and oral health-related quality of life: A review and network meta-analysis. 2022 All outcomes
Post-treatment (follow-up varied by trial) · Pediatric dental care; trials conducted in China, the USA, and Brazil
SMD -0.06 [-0.20, 0.08]
5 studies · 820 participants
GRADE not reported

Atraumatic restorative treatment vs placebo

Oral health-related quality of life · Children with dental caries

ART and placebo did not differ for oral health-related quality of life, based on an indirect network estimate with no direct trials (MD -0.01, 95% CI -0.40 to 0.38; ungraded).

1 finding from 1 review

Silver diamine fluoride and oral health-related quality of life: A review and network meta-analysis. 2022 All outcomes
Post-treatment · Pediatric dental care; trials conducted in China, the USA, and Brazil · Indirect network estimate (no direct trials)
MD -0.01 [-0.40, 0.38]
0 studies
GRADE not reported