Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

cART was associated with a significantly lower prevalence of oral candidiasis than monotherapy or dual therapy (very low certainty).

1 finding from 1 review

Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomes
Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries
OR 0.22 [0.16, 0.29]
4 studies
Very low

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

Oral candidiasis prevalence fell significantly after cART compared with before cART in the same children (very low certainty).

1 finding from 1 review

Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomes
After vs before cART (within-person) · Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries · post-cART vs pre-cART
OR 0.19 [0.15, 0.25]
Studies not reported
Very low

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

ART was associated with lower oral candidiasis prevalence.

1 finding from 1 review

Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomes
Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries
OR 0.35 [0.19, 0.63]
7 studies
Very low

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

cART was associated with a significantly lower prevalence of oral candidiasis in CLWH (very low certainty).

1 finding from 1 review

Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomes
Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries · cART
OR 0.35 [0.24, 0.51]
Studies not reported
Very low

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

Oral candidiasis prevalence did not differ significantly between treatment-naive CLWH and those on monotherapy or dual therapy (very low certainty).

1 finding from 1 review

Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomes
Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries · monotherapy or dual therapy
No significant difference in oral candidiasis prevalence was found between treatment-naive CLWH and those under monotherapy or dual therapy (no numeric estimate reported in the text).
Studies not reported
Very low