Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 4 · 66.7%Moderate 0 · 0%High 0 · 0%

Gonadotropins vs anti‐oestrogens

OHSS · intrauterine insemination (IUI) in women with infertility

Gonadotropins showed no clear difference in OHSS rate per couple compared with anti‐oestrogens (low certainty).

1 finding from 1 review

Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility 2021 · Cochrane Headline outcomes only
OR 0.77 [0.19, 3.14]
6 studies · 1482 participants
Low

Gonadotropins with GnRH agonists vs gonadotropins alone

OHSS · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotropins with GnRH agonists changes OHSS rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility 2021 · Cochrane Headline outcomes only
OR 1.8 [0.39, 8.32]
1 study · 60 participants
Very low

Gonadotropins with GnRH antagonist vs gonadotropins alone

OHSS · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotropins with GnRH antagonist changes OHSS rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility 2021 · Cochrane Headline outcomes only
OR 0.98 [0.12, 8.32]
5 studies · 1348 participants
Very low

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

OHSS · intrauterine insemination (IUI) in women with infertility

Aromatase inhibitors with gonadotropins showed no clear difference in OHSS rate per couple compared with anti‐oestrogens with gonadotropins (low certainty).

1 finding from 1 review

Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility 2021 · Cochrane Headline outcomes only
OR 4.45 [0.75, 26.43]
4 studies · 901 participants
Low

Gonadotrophins with anti‐oestrogens vs gonadotropins alone

OHSS · intrauterine insemination (IUI) in women with infertility

Gonadotrophins with anti‐oestrogens showed no clear difference in OHSS rate per couple compared with gonadotropins alone (low certainty).

1 finding from 1 review

Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility 2021 · Cochrane Headline outcomes only
OR 0.5 [0.04, 5.54]
1 study · 230 participants
Low

Aromatase inhibitors vs gonadotropins alone

OHSS · intrauterine insemination (IUI) in women with infertility

Aromatase inhibitors showed no clear difference in OHSS rate per couple compared with gonadotropins (low certainty).

1 finding from 1 review

Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility 2021 · Cochrane Headline outcomes only
OR 1 [0.14, 7.2]
2 studies · 680 participants
Low