Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Epilepsy

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 100%Moderate 0 · 0%High 0 · 0%

Topiramate plus ASMs vs placebo plus ASMs

Number of participants with ≥ 75% reduction in all seizures · Lennox‐Gastaut syndrome, any age

Topiramate plus ASMs showed no clear difference in number of participants with ≥ 75% reduction in all seizures compared with placebo plus ASMs (low certainty).

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
Peto OR 8.22 [0.6, 112.62]
1 study · 98 participants
Low