Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 3 reviews · Developmental, Psychosocial and Learning Problems

No studies found 1 · 20%GRADE not reported 0 · 0%Very low 3 · 60%Low 0 · 0%Moderate 1 · 20%High 0 · 0%

Music therapy vs placebo or usual care

Adverse events Any serious or non‐serious adverse event · Individuals with autism spectrum disorder

Music therapy showed no clear difference in adverse events Any serious or non‐serious adverse event compared with placebo therapy or standard care (moderate certainty).

1 finding from 1 review

Methylphenidate vs placebo or no intervention

Adverse events considered non‐serious (penicillin versus doxycycline) · Children and adolescents with ADHD

It is very uncertain whether methylphenidate changes proportion of participants with one or more adverse events… compared with placebo or no intervention (very low certainty).

1 finding from 1 review